In views of the fact that the cervical mucus is now being revealed to have a cyclic change as well as the endometrium under the control of ovarian hormone i. e. estrogen, progesterone, which in effect opens a way to be utilized in estimating the ovulation time, or as a mean of supplementary diagnosis for the anovulatory cycle, early pregnancy or ovarian and placental insufficiency etc, it is becoming to be subjected to one of the great concern in the field of gynecology.
From the observation of cyclical changes of the crystal pattern of the cervical mucus from the sample of 527 women, author attampted to classify the crystal . pattern, and divided the cycle in 5 periods.
From the sample of 410 women which comprises normal, pregnant. and lactating, author-has made a study on total amount, of cervical mucus, water content, dry weight, and organic and inorganic compound by means of microbalance, and the amount of sodium and potassium by means of flame photometer.
In addition the relationship between the content of cervical mucus and. the crystal picture was also being observed.
The followings were the main results of the findings obtained through this study.
1) The crystallization of the cervical mucus was divided into 9 patterns as(-), (SC+). (SC++), (SC+++), (SC+++)K, (DC+++), (DC++) (CE+), (DC+)(CE++), (CE+++). etc,
2) The menstrual cycle was classified into five periods according to the menstrual cycle day and crystallizat o n of the cervical mucus.(post menstrual, preovulatory, ovulatory, postovulatory and preme nstrual period).
3) In pregnant women,the apperance of the crystallization rated 40.5% in the 1st trimester, 27.4% in the 2nd trimester, 4.4% in the 3rd trimester and 20.9% among the total of pregent women.
This indicates that crystallization is most likely occur in the earlies stage of pregnancy.,
4) Crystallization appeared in two months after the delivery in case of lactating women.
5) The total amount of cervical mucus, water content, dry substance, organic and inorganic compound
were observed to have a cyclic change in paraell to the menstrual cycle.
6) The total amount of mucus, water content, dry substance, inorganic compound, sodium and potas sium have been observed to have a trend of ;beginning to increase at estrogen phase reaching .to the
maximmum in ovulation period and then substantially decrease in progesterone phase.
From the pregnant women, however, no particular trend such as indicated above could be observed. Variation in amount was practically more remarkable in case of lactating women..
7) It was revealed that the organic compound had tendency to reach the minimum at ovulations
period, while on the contrary it-increased at pregesterone phase.
As for the case of pregnant women, the amount of organic compound was obserbed to increase to 3 to 4 times (about 10 times in concentration) as much as that of menstrual cycle.
8) Amount of dry substance reached to the maximum in the ovulation period, and this was belived due to the increase in amount of inorganic compound.
It increased twice as much in pregnant women as in case of menstrual cycle, and again this was belived due to the increase in amount of organic compound.
9) An observation also revealed that the proportion of amount of organic and inorganic compounds plays a doninant role in crystallization, being supported by the fact that crystallization less likely occur as organic compound increases in amount.
10) Estreogen and progesterone suggested to have a close relation-ship with the crystal formation, as the former gives rise to the increase in total amount of cervical mucus, water content, inorganic compound, sodium and potassium while the latter does to the increased in amount: of organic compound.
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